Reaktion #1922868

Reaktionsgleichung

phloroglucinol

ethyl 2-(1-naphtylmethyl)-acetoacetate

HCl

→

5,7-dihydroxy-4-methyl-3-(1-naphtylmethyl)-2H-1-benzopyran-2-one

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigekept at that temperature overnight
2. 2
   SonstigeSolvent was evaporated
3. 3
   Sonstigethe precipitate triturated with water
4. 4
   Sonstigerecrystallized from isopropanol-water (1:1)

Vorschrift

A solution of phloroglucinol (0.47 g) and ethyl 2-(1-naphtylmethyl)-acetoacetate (1.00 g) in ethanol (20 ml) was treated with dry HCl at 0° C. for 3 hours and the solution kept at that temperature overnight. Solvent was evaporated and the precipitate triturated with water and recrystallized from isopropanol-water (1:1). Yield 0,96 g (78%). Melting point 275-280° C.

Quelle