Reaktion #1909799

Reaktionsgleichung

4-Phenylsulfanyl-[1,3]dioxolan-2-one

OXONE

water

→

4-benzenesulfonyl-[1,3]dioxolan-2-one

Lösungsmittel

methanol

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe obtained reaction mixture
2. 2
   workup.STIRRINGwas agitated at room temperature for 12 hours
3. 3
   Sonstigewas removed
4. 4
   workup.DISTILLATIONdecompression distillation
5. 5
   Extraktionthe resulting product was extracted
6. 6
   ExtraktionThe extracted organic solvent layer was again extracted
7. 7
   Sonstigewas removed
8. 8
   Sonstigeorganic solvent was removed
9. 9
   workup.DISTILLATIONdecompression distillation
10. 10
    SonstigeUsing silica gel chromatography, separation and purification

Vorschrift

4-Phenylsulfanyl-[1,3]dioxolan-2-one) was dissolved in methanol, and OXONE® was added. The resulting mixture was agitated at room temperature for 5 minutes and water was added. The obtained reaction mixture was agitated at room temperature for 12 hours. From the agitated reaction mixture, methanol was removed using decompression distillation and the resulting product was extracted using methylene chloride. The extracted organic solvent layer was again extracted using water, moisture was removed using magnesium sulfate, and then organic solvent was removed using decompression distillation. Using silica gel chromatography, separation and purification were performed to obtain a pure target product, 4-benzenesulfonyl-[1,3]dioxolan-2-one.

Quelle