Reaktion #1905523

ord-59a302560b404e7c9ee1406ed84cbda1

Reaktionsgleichung

O=Cc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea
Cl.O=C(OCc1ccccc1)C1CNCCO1
morpholine-2-carboxylic acid benzyl ester hydrochloride
→
O=C(O)C1CN(Cc2cnc(NC(=O)N(C3CCCCC3)C3CCCCC3)s2)CCO1
4-[2-(3,3-Dicyclohexyl-ureido)-thiazol-5-ylmethyl]-morpholine-2-carboxylic acid

Edukte

—
( F )
O=Cc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea
Cl.O=C(OCc1ccccc1)C1CNCCO1
morpholine-2-carboxylic acid benzyl ester hydrochloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigePrepared 11 mg (58%)

Vorschrift

Prepared 11 mg (58%) following the general procedures (P) and (F) using 1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea (70 mg. 0.21 mmol) and morpholine-2-carboxylic acid benzyl ester hydrochloride (77 mg, 0.30 mmol).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07598391B2uspto-grants-2009_10