Reaktion #1876820

Reaktionsgleichung

1,3,5-trihydroxyadamantane

trimethylamine

trimethylsilyl chloride

→

1,3-dihydroxy-5-trimethylsiloxyadamantane

Lösungsmittel

methylene chloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeReaction
2. 2
   Sonstigewas carried out at room temperature
3. 3
   SonstigeThe reaction product was partitioned by high performance liquid chromatography

Vorschrift

This 1,3,5-trihydroxyadamantane was dissolved in methylene chloride. To this solution were added a small amount of trimethylamine, and then an equimolar amount of trimethylsilyl chloride. Reaction was carried out at room temperature. The reaction product was partitioned by high performance liquid chromatography to obtain 1,3-dihydroxy-5-trimethylsiloxyadamantane.

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