Reaktion #1874367

ord-298630fe7309428287c3f2bda68e20da

Reaktionsgleichung

Cc1c2c(c(Cc3ccc(C(C)C)cc3)c(C)c1NCc1ccccc1)OCC2
N-benzyl-7-(4-isopropylbenzyl)-4,6-dimethyl-2,3-dihydro-1-benzofuran-5-amine
→
Cc1c(N)c(C)c(Cc2ccc(C(C)C)cc2)c2c1CCO2
title compound
Ausbeute 92.0%
Cc1c(N)c(C)c(Cc2ccc(C(C)C)cc2)c2c1CCO2
7-(4-Isopropylbenzyl)-4,6-dimethyl-2,3-dihydro-1-benzofuran-5-amine
Ausbeute 92.0%

Edukte

Cc1c2c(c(Cc3ccc(C(C)C)cc3)c(C)c1NCc1ccccc1)OCC2
N-benzyl-7-(4-isopropylbenzyl)-4,6-dimethyl-2,3-dihydro-1-benzofuran-5-amine

Reagenzien

Keine

Lösungsmittel

CCCCCC.CCOC(C)=O
ethyl acetate hexane

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigeobtained in Reference Example 271

Vorschrift

Using N-benzyl-7-(4-isopropylbenzyl)-4,6-dimethyl-2,3-dihydro-1-benzofuran-5-amine obtained in Reference Example 271, the title compound was synthesized in the same manner as in Reference Example 30. Yield 92%. Melting point: 114-115° C. (ethyl acetate-hexane).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07507841B2uspto-grants-2009_03