Reaktion #1870447

ord-869d5d2e367a4478bd6388917c4fbdfe

Reaktionsgleichung

OB(O)c1cccs1
2-thiopheneboronic acid
COC(=O)c1cc(C)cc(Br)c1
methyl 3-bromo-5-methylbenzoate
→
COC(=O)c1cc(C)cc(-c2ccsc2)c1
methyl 3-methyl-5-(3-thienyl)benzoate

Edukte

OB(O)c1cccs1
2-thiopheneboronic acid
COC(=O)c1cc(C)cc(Br)c1
methyl 3-bromo-5-methylbenzoate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Following the general procedure of EXAMPLE 766 and making non-critical variations but using 2-thiopheneboronic acid and methyl 3-bromo-5-methylbenzoate, methyl 3-methyl-5-(3-thienyl)benzoate is obtained.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07498436B2uspto-grants-2009_03