Reaktion #1869187

Reaktionsgleichung

Intermediate ( a )

4-[(2,2-Dimethyl-4,6-dioxo-[1,3]dioxan-5-ylidenemethyl)-amino]-benzonitrile

Dowtherm A

→

gold

Ausbeute 94.3%

4-Oxo-1,4-dihydro-quinoline-6-carbonitrile

Ausbeute 94.3%

Lösungsmittel

ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturAfter an additional five minutes at reflux
2. 2
   FiltrationThe product was filtered off
3. 3
   Waschenthoroughly washed with ether
4. 4
   Sonstigeair dried

Vorschrift

Intermediate (a) (27.5 g, 0.101 mol) was slowly added over five minutes to refluxing Dowtherm A (200 ml). After an additional five minutes at reflux, the mixture was allow to cool to room temperature then ether (200 ml) was added. The product was filtered off, thoroughly washed with ether then air dried to afford the product as a gold coloured solid (16.2 g, 94%).

Quelle