Reaktion #1869186

Reaktionsgleichung

4-amino-benzonitrile

2,2-dimethyl-[1,3]dioxane-4,6-dione

trimethylorthoformate

→

solid

Ausbeute 97.0%

4-[(2,2-Dimethyl-4,6-dioxo-[1,3]dioxan-5-ylidenemethyl)-amino]-benzonitrile

Ausbeute 97.0%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed for 3 hours
2. 2
   TemperaturAfter cooling the solid
3. 3
   Filtrationwas filtered off
4. 4
   Waschenwashed with ethanol and air
5. 5
   Sonstigedried

Vorschrift

A mixture of 4-amino-benzonitrile (12.5 g, 0.106 mol), 2,2-dimethyl-[1,3]dioxane-4,6-dione (18.3 g, 0.127 mol) and trimethylorthoformate (16 ml) in ethanol (100 ml) was refluxed for 3 hours. After cooling the solid was filtered off, washed with ethanol and air dried. The product was obtained as an off-white solid (27.9 g, 97%).

Quelle