Reaktion #1867145

Reaktionsgleichung

thionyl chloride

methanol

7-methoxy-1-oxo-1,2,3,4-tetrahydronaphthalene-2-acetic acid

→

methyl 7-methoxy-1-oxo-1,2,3,4-tetrahydronaphthalene-2-acetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturUnder cooling
2. 2
   workup.DISTILLATIONThe solvent was distilled off under reduced pressure

Vorschrift

Under cooling, 1.8 ml of thionyl chloride was dropwise added slowly to 20 ml of methanol. After 10 minutes, 1.5 g of 7-methoxy-1-oxo-1,2,3,4-tetrahydronaphthalene-2-acetic acid was added and stirred overnight at room temperature. The solvent was distilled off under reduced pressure to obtain 1.6 g of methyl 7-methoxy-1-oxo-1,2,3,4-tetrahydronaphthalene-2-acetate.

Quelle