Reaktion #1859536

Reaktionsgleichung

Compound 214

4-(4-chlorophenyl)-2,3,6,6,9-pentamethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine

racemic (1S,2R)-ethyl 1-amino-2-methylcyclopropanecarboxylate hydrochloride

1-aminocyclopropanecarboxylate hydrochloride

→

Racemic (1S,2R)-5′-(4-chlorophenyl)-2,6′,7′-trimethylspiro[cyclopropane-1,3′-thieno[2,3-e][1,4]diazepin]-2′(1′H)-one

Reaktionsbedingungen

Vorschrift

A procedure analogous to that set forth in the synthesis of Compound 214 was followed, with the exception that racemic (1S,2R)-ethyl 1-amino-2-methylcyclopropanecarboxylate hydrochloride was used as starting material instead of 1-aminocyclopropanecarboxylate hydrochloride. LRMS (M+H)+: 345 m/z.

Quelle