Reaktion #1853513

Reaktionsgleichung

4-chloro-2-methyl-benzothiazol-5-ylamine

4-chlorophenylacetyl chloride

triethylamine

→

N-(4-chloro-2-methyl-benzothiazol-5-yl)-2-(4-chloro-phenyl)-acetamide

Ausbeute 80.0%

Lösungsmittel

THF

Reaktionsbedingungen

Vorschrift

Reaction of 4-chloro-2-methyl-benzothiazol-5-ylamine (50 mg, 0.25 mmol) in THF (1.5 mL) with 4-chlorophenylacetyl chloride (65 mg, 0.30 mmol) in presence of triethylamine (42 μL, 0.30 mmol) according to method A gave N-(4-chloro-2-methyl-benzothiazol-5-yl)-2-(4-chloro-phenyl)-acetamide (65 mg, 0.19 mmol, 80% yield) as a white powder after crystallisation in hexane/DCM.

Quelle