Reaktion #1853505

Reaktionsgleichung

4-chloro-2-methyl-benzothiazol-5-ylamine

3,5-dichlorobenzoyl chloride

triethylamine

→

3,5-Dichloro-N-(4-chloro-2-methyl-benzothiazol-5-yl)-benzamide

Ausbeute 60.0%

Lösungsmittel

THF

Reaktionsbedingungen

Vorschrift

Reaction of 4-chloro-2-methyl-benzothiazol-5-ylamine (50 mg, 0.25 mmol) in THF (1.5 mL) with 3,5-dichlorobenzoyl chloride (122 mg, 0.56 mmol) in presence of triethylamine (0.5 mL) according to method A gave 3,5-Dichloro-N-(4-chloro-2-methyl-benzothiazol-5-yl)-benzamide (66 mg, 0.15 mmol, 60% yield) as a off-white powder after crystallisation in hexane/DCM.

Quelle