Reaktion #1849721

ord-90f2acb407b54655b4331a684a649e0f

Reaktionsgleichung

CCOCn1cnc2c1c(=O)n(CCCCC(C)=O)c(=O)n2C
7-ethoxymethyl-3-methyl-1-(5-oxohexyl)xanthine
[CH3][Mg][Cl]
methylmagnesium chloride
→
CCOCn1cnc2c1c(=O)n(CCCCC(C)(C)O)c(=O)n2C
7-Ethoxymethyl-1-(5-hydroxy-5-methylhexyl)-3-methylxanthine

Edukte

CCOCn1cnc2c1c(=O)n(CCCCC(C)=O)c(=O)n2C
7-ethoxymethyl-3-methyl-1-(5-oxohexyl)xanthine
[CH3][Mg][Cl]
methylmagnesium chloride

Reagenzien

Keine

Lösungsmittel

CCOCC
ether

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The compound was also obtained, for example, by Grignard synthesis from 7-ethoxymethyl-3-methyl-1-(5-oxohexyl)xanthine with methylmagnesium chloride in anhydrous ether analogously to Example 9.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04833146uspto-grants-1989_05