Reaktion #1846634

Reaktionsgleichung

2-nitro-1,3-dimethyl-5-tertiary-butyl-benzene

→

2,6-dimethyl-4-tertiary-butylaniline

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONwere charged 62 g
2. 2
   SonstigeThe autoclave was purged with hydrogen
3. 3
   Sonstigeat 90° C. to 95° C
4. 4
   FiltrationThe reaction mixture was filtered through Celite
5. 5
   Sonstigethe ethanol was evaporated
6. 6
   workup.DISTILLATIONThe final product was distilled at 93° C. to 98° C./7 to 10 torr
7. 7
   Sonstigeto yield 47.2 g

Vorschrift

To a 1 liter stirred autoclave were charged 62 g. (0.3 mole) of 2-nitro-1,3-dimethyl-5-tertiary-butyl-benzene, 300 ml. of ethanol and 1.0 g. of 5% palladium on charcoal. The autoclave was purged with hydrogen and then pressure to 1000 psig at 90° C. to 95° C. After 1 hour, the reaction was stopped. A total of 500 psig were taken up. The reaction mixture was filtered through Celite and the ethanol was evaporated. The final product was distilled at 93° C. to 98° C./7 to 10 torr to yield 47.2 g. of a very pale yellow liquid. An 89% isolated yield of 99+% pure 2,6-dimethyl-4-tertiary-butylaniline was obtained.

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