Reaktion #1835693

Reaktionsgleichung

8-(5-bromopyridin-2-yl)-1,4-dioxaspiro[4,5]decane-8-carbonitrile

5-bromo-2-(tetrahydro-2H-pyran-4-yl)pyridine

→

titled compound

8-(5-Aminopyridin-2-yl)-1,4-dioxaspiro[4,5]decane-8-carbonitrile

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigereacted
2. 2
   workup.ADDITIONtreated in a similar manner

Vorschrift

In Reference Example 75(4), 8-(5-bromopyridin-2-yl)-1,4-dioxaspiro[4,5]decane-8-carbonitrile described in Reference Example 82 was used in place of 5-bromo-2-(tetrahydro-2H-pyran-4-yl)pyridine, and reacted and treated in a similar manner to give the titled compound.

Quelle