Reaktion #1823932

ord-24cbf639a4f34197891e3e5b21c1d8ba

Reaktionsgleichung

CC(C)(C)OC(=O)c1ccccc1-c1ccc(Cn2c(-c3ccccn3)nc3ccccc32)cc1
tert.butyl 4'-[(2-(2-pyridyl)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate
O=C(O)C(F)(F)F
trifluoroacetic acid
→
O=C(O)c1ccccc1-c1ccc(Cn2c(-c3ccccn3)nc3ccccc32)cc1
4'-[(2-(2-Pyridyl)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylic acid

Edukte

CC(C)(C)OC(=O)c1ccccc1-c1ccc(Cn2c(-c3ccccn3)nc3ccccc32)cc1
tert.butyl 4'-[(2-(2-pyridyl)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate
O=C(O)C(F)(F)F
trifluoroacetic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-(2-pyridyl)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05541229uspto-grants-1996_07