Reaktion #1819880

Reaktionsgleichung

4-piperidone hydrochloride

benzoxazepine

7-chloro-1,2,3,5-tetrahydro-1-nitroso-4,1-benzoxazepine

→

title compound

6-chloro-1,2,8,9,10,11-hexahydro-4H-pyrido[3',4':4,5]pyrrolo[3,2,1-jk][4,1]benzoxazepine hydrochloride

Reaktionsbedingungen

Vorschrift

By the procedure described in Example 1, the appropriate benzoxazepine is converted to 7-chloro-1,2,3,5-tetrahydro-1-nitroso-4,1-benzoxazepine, m.p. 54°-56°. The latter is reduced to the corresponding 1-amino derivative hydrochloride, which is reacted with 4-piperidone hydrochloride to yield the title compound, m.p. 304°-305°.

Quelle