Reaktion #1817649

Reaktionsgleichung

α-phenyl-o-toluidine

trimethyl orthoformate

aminoacetaldehyde

→

1-(α-phenyl-o-tolyl)imidazole

Lösungsmittel

monoglyme

Reaktionsbedingungen

Vorschrift

In the manner given in Example 1, α-phenyl-o-toluidine is reacted first with trimethyl orthoformate; the resulting product is reacted with aminoacetaldehyde, dimethyl acetal, and the resulting product of this reaction is heated with titanium tetrachloride in monoglyme to give 1-(α-phenyl-o-tolyl)imidazole.

Quelle