Reaktion #1811

Reaktionsgleichung

ammonia

isothiocyanatoacetaldehyde dimethyl acetal

→

title compound

N-(2,2-Dimethoxyethyl)thiourea

Lösungsmittel

Methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   EinengenThe mixture was concentrated
2. 2
   Sonstigethe residue was chromatographed (silica gel, 5% methanol/dichloromethane)

Vorschrift

Methanol (200 mL) was saturated with ammonia and stirred with isothiocyanatoacetaldehyde dimethyl acetal (5.0 g) for 2 h. The mixture was concentrated and the residue was chromatographed (silica gel, 5% methanol/dichloromethane) to give the title compound.

Quelle