Reaktion #1810806

ord-26d5dd4e7ab34ea3bd1bf925f10025a1

Reaktionsgleichung

CN=C=S
Methyl-isothiocyanate
CN(C)[C@H]1CC[C@H](N)CC1
trans-4-dimethylamino-cyclohexanamine
→
CNC(=S)NC1CCC(N(C)C)CC1
1-(4-dimethylaminocyclohexyl)-3-methyl-thiourea

Edukte

CN=C=S
Methyl-isothiocyanate
CN(C)[C@H]1CC[C@H](N)CC1
trans-4-dimethylamino-cyclohexanamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe mixture obtained
  2. 2
    Sonstigesolvent is evaporated

Vorschrift

0.90 g of Methyl-isothiocyanate are added to a solution of 1.74 g of trans-4-dimethylamino-cyclohexanamine in 50 ml of EtAc. The mixture obtained is stirred at RT, solvent is evaporated and 1-(4-dimethylaminocyclohexyl)-3-methyl-thiourea is obtained.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07485632B2uspto-grants-2009_02