Reaktion #1787463

Reaktionsgleichung

4-(N-methylpiperidin-4-yl)oxy-3-trifluoromethyl-1-nitrobenzene

hydrogen

→

4-(N-methylpiperidin-4-yl)oxy-3-trifluoromethylbenzenamine

Lösungsmittel

methanol

Pd/C

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe catalyst was filtered off
2. 2
   Einengenthe filtrate was concentrated

Vorschrift

4-(N-methylpiperidin-4-yl)oxy-3-trifluoromethyl-1-nitrobenzene was dissolved in methanol in the presence of Pd/C. The solution was hydrogenated at 50 psi for 1 hour until hydrogen intake was completed. The catalyst was filtered off and the filtrate was concentrated to afford 4-(N-methylpiperidin-4-yl)oxy-3-trifluoromethylbenzenamine, >95%.

Quelle