Reaktion #1780321

Reaktionsgleichung

5-fluoro-3-isobutyl-benzo[b]thiophene-2-sulfonyl chloride

2-amino-5-bromobenzotrifluoride

→

desired compound

5-Fluoro-3-isobutyl-benzo[b]thiophene-2-sulfonic acid(4-bromo-2-trifluoromethyl-phenyl)-amide

Lösungsmittel

pyridine

Reaktionsbedingungen

Vorschrift

This compound was prepared in analogy to Example 1 starting from 5-fluoro-3-isobutyl-benzo[b]thiophene-2-sulfonyl chloride (044 g), 2-amino-5-bromobenzotrifluoride (3.44 g) in pyridine (5 ml) for 18 h at rt to obtain the desired compound (0.24 g) as a colorless solid. MS (ISN): 508.2, 510.3 (M−H)−

Quelle