Reaktion #1771990

ord-56238b79bf8e4876a8c816dff94dc2f6

Reaktionsgleichung

CC1(C)CN(C(=O)OC(C)(C)C)[C@@](C(=O)O)(C(C)(C)C)C1
tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline
→
CC1(C)CN[C@H](C(=O)O)C1
4,4-Dimethylproline

Edukte

CC1(C)CN(C(=O)OC(C)(C)C)[C@@](C(=O)O)(C(C)(C)C)C1
tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline

Reagenzien

Keine

Lösungsmittel

ClCCl
dichloromethane

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    EinengenThe solution was concentrated
  2. 2
    Sonstigedried under high vacuum
  3. 3
    Sonstigetaken to the next step without further purification

Vorschrift

A solution of tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline in dichloromethane (5 mL) and trifluoroacetic (5 mL) was stirred at room temperature for five hours. The solution was concentrated, dried under high vacuum and taken to the next step without further purification.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: USRE043298E1uspto-grants-2012_04