Reaktion #1768456

ord-dc5e465f3d5545bab9192dbb8863fe65

Reaktionsgleichung

C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)CO
monoolein
CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)CO
monoolein
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
→
CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)CO.C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
Monoolein Taurocholic acid

Edukte

C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)CO
monoolein
CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)CO
monoolein
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid

Reagenzien

Keine

Lösungsmittel

O
water

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigewas stored at 10° C.

Vorschrift

860 mg of taurocholic acid was dissolved in 40 ml of de-ionized water. Then, 570.6 mg of monoolein was slowly added to the taurocholic acid solution using an ice bath on a sonic mixer. The final monolein and taurocholic acid concentration was 40 mM (the molecular weight of taurocholic acid is 537.7 and that of monoolein is 356.5). The mixture was stored at 10° C. until used.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05169944uspto-grants-1992_12