Reaktion #1754839

Reaktionsgleichung

3-(4-chloro-phenyl)-3-oxo-propionitrile

sulfuric acid

→

3-(4-chloro-phenyl)-3-oxo-propionamide

Lösungsmittel

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe precipitate was collected by filtration
2. 2
   Waschenwashed with water
3. 3
   Sonstigedried under reduced pressure

Vorschrift

The crude 3-(4-chloro-phenyl)-3-oxo-propionitrile obtained above was stirred with 100 mL of sulfuric acid at room temperature for 4 hours. The mixture was poured into 500 mL of ice-water and stirred for 30 minutes. The precipitate was collected by filtration, washed with water and dried under reduced pressure to give 5.73 g of 3-(4-chloro-phenyl)-3-oxo-propionamide as a brown solid which was used in next step without further purification.

Quelle