Reaktion #1751

ord-65d0d248651b4777b9672b8046a54da0

Reaktionsgleichung

CN(C)Cc1ccc([C@H]2CC[C@H](O)CC2)cc1
trans-4-(4-dimethylaminomethylphenyl)-cyclohexanol
CCN(CC)CC.O=C(Cl)C1CCCCC1
cyclohexane carboxylic acid chloride triethylamine
→
CN(C)Cc1ccc([C@H]2CC[C@H](OC(=O)C3CCCCC3)CC2)cc1
trans-O-cyclohexanoyl-4-(4-dimethylaminomethylphenyl)-cyclohexanol

Edukte

CN(C)Cc1ccc([C@H]2CC[C@H](O)CC2)cc1
trans-4-(4-dimethylaminomethylphenyl)-cyclohexanol
CCN(CC)CC.O=C(Cl)C1CCCCC1
cyclohexane carboxylic acid chloride triethylamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

from trans-4-(4-dimethylaminomethylphenyl)-cyclohexanol and cyclohexane carboxylic acid chloride/triethylamine. White crystals.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05726205uspto-grants-1998_03