Reaktion #1748446

ord-ac882ad947f548508d097f7f4af1f852

Reaktionsgleichung

CON(C)C(=O)c1cn(-c2cccc(-c3ccccc3Cl)c2)cn1
compound 12e
CON(C)C(=O)c1cn(-c2cccc(-c3ccccc3Cl)c2)cn1
1-(2′-Chloro-biphenyl-3-yl)-1H-imidazole-4-carboxylic acid methoxy-methyl-amide
Fc1cccc(Br)c1
1-bromo-3-fluorobenzene
→
O=C(c1cccc(F)c1)c1cn(-c2cccc(-c3ccccc3Cl)c2)cn1
[1-(2′-Chloro-biphenyl-3-yl)-1H-imidazol-4-yl]-(3-fluoro-phenyl)-methanone

Edukte

CON(C)C(=O)c1cn(-c2cccc(-c3ccccc3Cl)c2)cn1
compound 12e
CON(C)C(=O)c1cn(-c2cccc(-c3ccccc3Cl)c2)cn1
1-(2′-Chloro-biphenyl-3-yl)-1H-imidazole-4-carboxylic acid methoxy-methyl-amide
Fc1cccc(Br)c1
1-bromo-3-fluorobenzene

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThis compound is prepared by method C

Vorschrift

This compound is prepared by method C using compound 12e and 1-bromo-3-fluorobenzene

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08030339B2uspto-grants-2011_10