Reaktion #1748411

ord-b34477c87c9c4863bb91a47844e83998

Reaktionsgleichung

COc1ccc(F)cc1-c1cccc(-n2cnc(C(=O)N(C)OC)c2)c1
compound 12b
COc1ccc(F)cc1-c1cccc(-n2cnc(C(=O)N(C)OC)c2)c1
1-(5′-Fluoro-2′-methoxy-biphenyl-3-yl)-1H-imidazole-4-carboxylic acid methoxy-methyl-amide
c1cscn1
thiazole
→
COc1ccc(F)cc1-c1cccc(-n2cnc(C(=O)c3nccs3)c2)c1
[1-(5′-Fluoro-2′-methoxy-biphenyl-3-yl)-1H-imidazol-4-yl]-thiazol-2-yl-methanone

Edukte

COc1ccc(F)cc1-c1cccc(-n2cnc(C(=O)N(C)OC)c2)c1
compound 12b
COc1ccc(F)cc1-c1cccc(-n2cnc(C(=O)N(C)OC)c2)c1
1-(5′-Fluoro-2′-methoxy-biphenyl-3-yl)-1H-imidazole-4-carboxylic acid methoxy-methyl-amide
c1cscn1
thiazole

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThis compound was prepared by method C

Vorschrift

This compound was prepared by method C using compound 12b and thiazole.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08030339B2uspto-grants-2011_10