Reaktion #1734015

Reaktionsgleichung

4'-octyloxy-3,3'-difluorobiphenol

1-bromooctane

4-benzyloxy-3-fluoro-brombenzene

potassium carbonate

3-fluoro-4-octyloxyphenyl boronic acid

→

required product

4,4'-dioctyloxy-3,3'-difluorobiphenyl

Lösungsmittel

butanone

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeobtained
2. 2
   Temperaturis heated
3. 3
   Temperaturunder reflux
4. 4
   TemperaturAfter cooling the reaction mixture
5. 5
   Filtrationis filtered
6. 6
   Sonstigethe filtrate evaporated off
7. 7
   workup.DISTILLATIONdistillation under reduced pressure

Vorschrift

A mixture of 4'-octyloxy-3,3'-difluorobiphenol (0.1 mol, obtained by coupling 3-fluoro-4-octyloxyphenyl boronic acid with 4-benzyloxy-3-fluoro-brombenzene followed by hydrogenolytic cleavage of the benzylic ether), 1-bromooctane (0.12 mol), potassium carbonate (30 g) and butanone (125 ml) is heated under reflux and stirred for 20 hrs. After cooling the reaction mixture is filtered and the filtrate evaporated off, distillation under reduced pressure affords the required product, m.p. 84°.

Quelle