Reaktion #1732690

Reaktionsgleichung

6-((benzyloxy)methyl)-5,7-dioxaspiro[2.5]octane

hydrogen

→

title compound

Ausbeute 98.7%

5,7-dioxaspiro[2.5]oct-6-ylmethanol

Ausbeute 98.7%

Lösungsmittel

ethyl acetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe reaction vessel was purged with nitrogen
2. 2
   Filtrationthe catalyst was filtered off
3. 3
   workup.DISTILLATIONthe solvent was distilled off

Vorschrift

The 6-((benzyloxy)methyl)-5,7-dioxaspiro[2.5]octane (6.1 g, 26 mmol) obtained by the step (2a) was mixed with 20% palladium hydroxide (800 mg) and ethyl acetate (70 ml) and the mixture was stirred in a hydrogen atmosphere for 24 hours. The reaction vessel was purged with nitrogen and the catalyst was filtered off and then the solvent was distilled off to obtain the title compound (3.7 g, yield: 98.7%) as a colorless oil.

Quelle