Reaktion #1732684

Reaktionsgleichung

2-((benzyloxy)methyl)-5,5-dimethyl-1,3-dioxane

hydrogen

hydrogen

→

title compound

Ausbeute 85.0%

(5,5-dimethyl-1,3-dioxan-2-yl)methanol

Ausbeute 85.0%

Lösungsmittel

ethyl acetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe reaction vessel was purged with nitrogen
2. 2
   Filtrationthe catalyst was filtered off
3. 3
   workup.DISTILLATIONthe solvent was distilled off

Vorschrift

The 2-((benzyloxy)methyl)-5,5-dimethyl-1,3-dioxane (7.6 g, 32.2 mmol) obtained by the step (1a) was mixed with 20% palladium hydroxide (700 mg) and ethyl acetate (70 ml). The mixture was stirred in a hydrogen atmosphere overnight. The reaction mixture was allowed to stand for further 5 days in the same hydrogen atmosphere. The reaction vessel was purged with nitrogen, the catalyst was filtered off, and the solvent was distilled off to obtain the title compound (4 g, yield: 85%) as a white solid.

Quelle