Reaktion #1730052

Reaktionsgleichung

5-(4-ethylphenyl)-1-(morpholin-4-ylcarbonyl)piperidine-3-carboxylic acid

5-(4-Ethylphenyl)-1-(morpholin-4-ylcarbonyl)piperidine-3-carboxylic acid

N′-hydroxy-3-methoxybenzenecarboximidamide

→

4-({3-(4-Ethylphenyl)-5-[3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}carbonyl)-morpholine

Reaktionsbedingungen

Vorschrift

69 mg (0.20 mmol) of 5-(4-ethylphenyl)-1-(morpholin-4-ylcarbonyl)piperidine-3-carboxylic acid (Example 38A) and 37 mg (0.22 mmol, 1.2 eq.) of N′-hydroxy-3-methoxybenzenecarboximidamide were reacted according to the General Method 1. Yield:

Quelle