Reaktion #1726698
ord-89517c2aef894390b29f68af5590b7b2
Reaktionsgleichung
orthoformic acid triethyl ester
4-phenyl-2H-pyrazol-3-ylamine
benzeneacetonitrile
→
3-oxo-2-phenyl-propionitrile
Edukte
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
4-Aryl-3-aminopyrazoles such as 4-phenyl-2H-pyrazol-3-ylamine may be prepared according to the procedures described in patent EP269,859 and illustrated in scheme 8, by reacting benzeneacetonitrile with orthoformic acid triethyl ester to give 3-oxo-2-phenyl-propionitrile which is reacted with hydrazine.