Reaktion #172591

Reaktionsgleichung

4-(N,N-diphenylamino)benzaldehyde

→

Benz[f]indane-1,3-dione

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturunder reflux for 6 hours
2. 2
   Sonstigethe obtained crystal was separated by filtration
3. 3
   Waschenwashed
4. 4
   Sonstigerecrystallized from chloroform-acetonitrile

Vorschrift

Benz[f]indane-1,3-dione was synthesized according to J. Med. Chem., Vol. 16, paragraphs 1334 to 1339 (1973), and 2 g of this sample and 3.1 g of 4-(N,N-diphenylamino)benzaldehyde were heated with stirring in 20 ml of ethanol under reflux for 6 hours. After cooling to room temperature, the obtained crystal was separated by filtration, washed and recrystallized from chloroform-acetonitrile to obtain 4.3 g of Compound (1).

Quelle