Reaktion #172500

Reaktionsgleichung

8-methoxy-2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolizine-9-carboaldehyde

2-(3-cyano-4,5,5-trimethyl-2(5H)-furanylidene)propanedinitrile

→

2-[3-cyano-4-[2-(8-methoxy-2,3,6,7-tetrahydro-1H,5H-benzo [ij]quinolizine-9-yl)vinyl]-5,5-dimethyl-2(5H)-furanylidene]propanedinitrile

Ausbeute 85.2%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe precipitate was separated by filtration
2. 2
   Waschenwashed with methanol
3. 3
   SonstigeThe crystal was purified by silica gel column chromatography
4. 4
   Waschenwashed with methanol
5. 5
   Sonstigeto give 228 mg of a dark blue crystal
6. 6
   Sonstigeamp of 250-252° C. (yield: 85.2%)

Vorschrift

In 5 ml of ethanol were dissolved 150 mg (0.65 mmol) of 8-methoxy-2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolizine-9-carboaldehyde and 142 mg (0.71 mmol) of 2-(3-cyano-4,5,5-trimethyl-2(5H)-furanylidene)propanedinitrile. The mixture was stirred at room temperature for 3 hours and further at 50° C. for 3 hours. The precipitate was separated by filtration and washed with methanol. The crystal was purified by silica gel column chromatography and washed with methanol to give 228 mg of a dark blue crystal having amp of 250-252° C. (yield: 85.2%).

Quelle