Reaktion #1719462

ord-854325be44884b5b9d70cc1389794711

Reaktionsgleichung

CC(=O)Oc1cc(C(=O)O)cc(OC(C)=O)c1OC(C)=O
3,4,5-triacetoxybenzoic acid
O=S(Cl)Cl
thionyl chloride
→
CC(=O)Oc1cc(C(=O)Cl)cc(OC(C)=O)c1OC(C)=O
desired product
Ausbeute 102.0%
CC(=O)Oc1cc(C(=O)Cl)cc(OC(C)=O)c1OC(C)=O
3,4,5-triacetoxybenzoic acid chloride
Ausbeute 102.0%

Edukte

CC(=O)Oc1cc(C(=O)O)cc(OC(C)=O)c1OC(C)=O
3,4,5-triacetoxybenzoic acid
O=S(Cl)Cl
thionyl chloride

Reagenzien

Keine

Lösungsmittel

ClCCCl
1,2-dichloroethane

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    workup.DISTILLATIONThe excess thionyl chloride and 1,2-dichloroethane were distilled away under reduced pressure

Vorschrift

In 100 ml of 1,2-dichloroethane, 57 g (0.19 mol) of 3,4,5-triacetoxybenzoic acid and 34 g (0.29 mol) of thionyl chloride were reacted at 60° C. for 2 hours. The excess thionyl chloride and 1,2-dichloroethane were distilled away under reduced pressure to obtain 61 g of the desired product.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04474874uspto-grants-1984_10