Reaktion #171578

Reaktionsgleichung

1,1′-Thiocarbonyldiimidazole

N-phenylethylenediamine

DCM

→

title compound 301

Ausbeute 35.3%

1-phenylimidazolidine-2-thione

Ausbeute 35.3%

Lösungsmittel

THF

Reaktionsbedingungen

Aufarbeitung

1. 1
   Waschenthe solution was washed with 1N HCl
2. 2
   Trocknendried over anhydrous sodium sulfate
3. 3
   Einengenconcentrated under reduced pressure

Vorschrift

1,1′-Thiocarbonyldiimidazole (4.51 g, 25.3 mmol) was added to a solution of N-phenylethylenediamine (3 mL, 23.02 mmol) in THF (230 mL) and the mixture was stirred for 2 h at room temperature. DCM was added and the solution was washed with 1N HCl, dried over anhydrous sodium sulfate and concentrated under reduced pressure affording title compound 301 (1.45 g, 8.13 mmol, 35.3% yield). m/z: 179.1 (M+H)+

Quelle