Reaktion #170976

Reaktionsgleichung

Methyl (4-nitrophenoxy)acetate

Methyl (4-Nitro phenoxy)acetate

→

22

Ausbeute 92.1%

(4-Nitrophenoxy)acetic acid

Ausbeute 92.1%

Lösungsmittel

HCl

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationcrude 22 was filtered
2. 2
   Sonstigedried
3. 3
   Sonstigerecrystallised from a mixture of ethyl acetate:hexane (1:5)

Vorschrift

Methyl (4-nitrophenoxy)acetate 7 (100 g, 474 mmol) was refluxed in conc. HCl (1 L) for 8 hours. The reaction mass was cooled to room temperature and crude 22 was filtered, dried and recrystallised from a mixture of ethyl acetate:hexane (1:5) to give pure 22 (86 g, 92.1%) as a white shining powder with an m.p. between 186-188.5° C.

Quelle