Reaktion #1707704

Reaktionsgleichung

4-thioxo-1,3-thiazolidin-2-one

2-(2-methoxyethoxy)ethanamine

→

title compound

Ausbeute 84.4%

4-{[2-(2-methoxyethoxy)ethyl]amino}-1,3-thiazol-2(5H)-one

Ausbeute 84.4%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solvent was evaporated under reduced pressure
2. 2
   Sonstigethe residue was purified by silica gel column chromatography (ethyl acetate)

Vorschrift

To a solution of 4-thioxo-1,3-thiazolidin-2-one (2.24 g) in ethanol (20 mL) was added 2-(2-methoxyethoxy)ethanamine (2.5 g), and the mixture was stirred at room temperature for 5 hr. The solvent was evaporated under reduced pressure, and the residue was purified by silica gel column chromatography (ethyl acetate) to give the title compound (3.1 g).

Quelle