Reaktion #170586

Reaktionsgleichung

N,N-dimethylformamide dimethylacetal

methylglyoxal 1,1-dimethylacetal

isobutanol

→

title product

Ausbeute 48.0%

(E)-4-Dimethylamino-1,1-dimethoxy-but-3-en-2-one

Ausbeute 48.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe mixture was then cooled
2. 2
   Sonstigeevaporated
3. 3
   SonstigePurification
4. 4
   workup.DISTILLATIONby distillation

Vorschrift

A mixture of N,N-dimethylformamide dimethylacetal (86.0 g, 584 mmol) and methylglyoxal 1,1-dimethylacetal (85.6 g, 724 mmol) in isobutanol (500 mL) was heated at 100° C. overnight. The mixture was then cooled and evaporated. Purification by distillation afforded the title product (49.9 g, 48%) as an orange liquid. Bp 123-124° C. at 0.9 mbar. MS: m/e=174.4 [M+H]|.

Quelle