Reaktion #170523

Reaktionsgleichung

6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid

2-methyl-pyrrolidine

→

title compound

Ausbeute 99.0%

[6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-pyridin-3-yl]-(2-methyl-pyrrolidin-1-yl)-methanone

Ausbeute 99.0%

Reaktionsbedingungen

Vorschrift

As described for example 191, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (200 mg, 0.64 mmol) was converted, using 2-methyl-pyrrolidine instead of 2-aminoethyl isopropylether, to the title compound (240 mg, 99%) which was obtained as a colourless. MS: m/e=378.3 [M+H]+.

Quelle