Reaktion #1702112

Reaktionsgleichung

2-(3-nitrophenyl)ethanol

→

desired product

Ausbeute 99.0%

2-(3-Aminophenyl)ethanol

Ausbeute 99.0%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigewas hydrogenated at 45 psi overnight
2. 2
   FiltrationThe resultant mixture was filtered
3. 3
   Einengenconcentrated

Vorschrift

Into a pressure bottle were added 2-(3-nitrophenyl)ethanol (3.0 g, 18 mmol) and methanol (100 mL) and 10% palladium on carbon (0.1 g, 0.08 mmol). The reaction mixture was hydrogenated at 45 psi overnight. The resultant mixture was filtered and concentrated to provide the desired product (2.44 g, 99%) as a white solid. LCMS for C8H12NO (M+H)+: m/z=138.1.

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