Reaktion #170203

Reaktionsgleichung

bromine

2-amino-3-pyridinecarboxaldehyde

→

title compound

Ausbeute 165.3%

2-Amino-5-bromonicotinaldehyde hydrobromide

Ausbeute 165.3%

Lösungsmittel

acetic acid

acetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe resulting precipitate was filtered
2. 2
   Waschenwashed with diethyl ether

Vorschrift

A solution of bromine (1.05 mL, 20.0 mmol) in acetic acid (20 mL) was added to a solution of 2-amino-3-pyridinecarboxaldehyde (2.5 g, 20 mmol) in acetic acid (50 mL) at room temperature. The reaction mixture was then stirred overnight. The resulting precipitate was filtered and washed with diethyl ether to give the title compound as a white solid (4.66 g, 80%).

Quelle