Reaktion #170105

Reaktionsgleichung

tert-butyl 3-phenoxypyrrolidine-1-carboxylate

tert-Butyl 3-phenoxypyrrolidine-1-carboxylate

HCl

→

title compound

3-Phenoxypyrrolidine hydrochloride

Lösungsmittel

dichloromethane

dioxane

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solvent was evaporated under reduced pressure

Vorschrift

To a cooled solution of tert-butyl 3-phenoxypyrrolidine-1-carboxylate (172 mg, 0.65 mmol; which may be prepared as described in Step 2) in dichloromethane (4.3 mL) was added dropwise HCl 4N in dioxane (3.2 mL). The solution was warmed to room temperature and stirred for 1 h. The solvent was evaporated under reduced pressure to give the title compound (135 mg, quantitative) as an orange oil.

Quelle