Reaktion #1683340

ord-318f3bb74ab74ad8a1a3711688d53460

Reaktionsgleichung

CCCCCCCC/C=C\CCCCCCCCN(CCCCCCCC/C=C\CCCCCCCC)C(=O)CBr
2-bromo-N,N-dioleylacetamide
[I-].[Na+]
sodium iodide
CCCCCC
Hexane
→
CCCCCCCC/C=C\CCCCCCCCN(CCCCCCCC/C=C\CCCCCCCC)C(=O)CI
2-Iodo-N,N-dioleylacetamide

Edukte

CCCCCCCC/C=C\CCCCCCCCN(CCCCCCCC/C=C\CCCCCCCC)C(=O)CBr
2-bromo-N,N-dioleylacetamide
[I-].[Na+]
sodium iodide
CCCCCC
Hexane

Reagenzien

Keine

Lösungsmittel

CC(C)=O
acetone

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Filtrationthe precipitate is filtered off
  2. 2
    Sonstigeto give
  3. 3
    Sonstigeafter evaporating the filtrate under reduced pressure, 2-iodo-N,N-dioleylacetamide (0.87 g; 100%) in the form of a yellowish liquid

Vorschrift

A solution of 2-bromo-N,N-dioleylacetamide (0.81 g; 1.27 mmol) and sodium iodide (0.76 g; 5.08 mmol) in acetone is refluxed overnight. Hexane (10 ml) is added and the precipitate is filtered off to give, after evaporating the filtrate under reduced pressure, 2-iodo-N,N-dioleylacetamide (0.87 g; 100%) in the form of a yellowish liquid.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06291423B1uspto-grants-2001_09