Reaktion #168063

ord-fa2c8ae6bd9046c998b5515af50314ae

Reaktionsgleichung

FC(F)(F)c1ccc(-c2ccc(Cl)nn2)cc1
3-chloro-6-(4-trifluoromethylphenyl)pyridazine
CN1CCCC(CN2CCNCC2)C1
(1-methylpiperidin-3-ylmethyl)piperazine
→
CN1CCCC(CN2CCN(c3ccc(-c4ccc(C(F)(F)F)cc4)nn3)CC2)C1
title compound
CN1CCCC(CN2CCN(c3ccc(-c4ccc(C(F)(F)F)cc4)nn3)CC2)C1
3-[4-(1-Methylpiperidin-3-ylmethyl)piperazin-1-yl]-6-(4-trifluoromethylphenyl)pyridazine

Edukte

FC(F)(F)c1ccc(-c2ccc(Cl)nn2)cc1
3-chloro-6-(4-trifluoromethylphenyl)pyridazine
CN1CCCC(CN2CCNCC2)C1
(1-methylpiperidin-3-ylmethyl)piperazine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared by a similar procedure to that described in Example 1, starting from 3-chloro-6-(4-trifluoromethylphenyl)pyridazine and (1-methylpiperidin-3-ylmethyl)piperazine.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08846677B2uspto-grants-2014_09