Reaktion #168057

ord-4f03468750b84695917ef2c17f8d51c6

Reaktionsgleichung

CC(=O)c1ccc(-c2ccc(Cl)nc2)cc1
2-chloro-5-(4-acetylphenyl)pyridine
C1CCC(N2CCNCC2)C1
1-cyclopentylpiperazine
→
CC(=O)c1ccc(-c2ccc(N3CCN(C4CCCC4)CC3)nc2)cc1.Cl.Cl
title compound
CC(=O)c1ccc(-c2ccc(N3CCN(C4CCCC4)CC3)nc2)cc1.Cl.Cl
1-{4-[6-(4-Cyclopentylpiperazin-1-yl)pyridin-3-yl]phenyl}ethanone, dihydrochloride

Edukte

CC(=O)c1ccc(-c2ccc(Cl)nc2)cc1
2-chloro-5-(4-acetylphenyl)pyridine
C1CCC(N2CCNCC2)C1
1-cyclopentylpiperazine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared by a similar procedure to that described in Example 1, starting from 2-chloro-5-(4-acetylphenyl)pyridine and 1-cyclopentylpiperazine.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08846677B2uspto-grants-2014_09