Reaktion #167834

Reaktionsgleichung

Intermediate 17

cis-1-(5-ethylpyrimidin-2-yl)-3-fluoropiperidin-4-ol

1-(4-((2H-1,2,3-triazol-4-yl)methoxy)-3-fluorophenyl)-1H-tetrazole

Intermediate 16

1-(4-((2H-1,2,3-triazol-4-yl)methoxy)-3-fluorophenyl)-1H-tetrazole

cis-1-(5-ethylpyrimidin-2-yl)-3-fluoropiperidin-4-ol

→

title compound

5-Ethyl-2-((trans)-3-fluoro-4-(4-((2-fluoro-4-(1H-tetrazol-1-yl)phenoxy)methyl)-2H-1,2,3-triazol-2-yl)piperidin-1-yl)pyrimidine

Reaktionsbedingungen

Vorschrift

The title compound was synthesized using 1-(4-((2H-1,2,3-triazol-4-yl)methoxy)-3-fluorophenyl)-1H-tetrazole (Intermediate 16) and cis-1-(5-ethylpyrimidin-2-yl)-3-fluoropiperidin-4-ol (Intermediate 17) in a manner similar to that described in Example 29.

Quelle