Reaktion #167655

Reaktionsgleichung

methyl 5-(2,2-difluoroethoxy)-2-nitrobenzoate

Methyl 5-(2,2-difluoroethoxy)-2-nitrobenzoate

EtOH

AcOH

→

Methyl 2-amino-5-(2,2-difluoroethoxy)benzoate

Lösungsmittel

AcOEt

Reaktionsbedingungen

Vorschrift

21 g of methyl 5-(2,2-difluoroethoxy)-2-nitrobenzoate obtained in stage 3.1 and 1 g of Pd/C (10%) in a mixture of 300 ml of AcOEt, 50 ml of EtOH and 5 ml of AcOH are stirred at AT under a hydrogen atmosphere for 24 h 00.

Quelle