Reaktion #167627

ord-80f121123eba4faaa83f2ae4e63a6962

Reaktionsgleichung

Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
product
Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
4-(5-Bromopyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane
N#Cc1cccc(B(O)O)c1
3-cyanophenylboronic acid
→
N#Cc1cccc(-c2cncc(N3CC4CC5CC3CN(C5)C4)c2)c1
title compound
N#Cc1cccc(-c2cncc(N3CC4CC5CC3CN(C5)C4)c2)c1
3-[5-(1,4-diazatricyclo[4.3.1.13,8]undec-4-yl)pyridin-3-yl]benzonitrile

Edukte

Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
product
Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
4-(5-Bromopyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane
N#Cc1cccc(B(O)O)c1
3-cyanophenylboronic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from the product of Example 65A and 3-cyanophenylboronic acid according to General Method B: LC-MS Method D (ESI+) m/z 331.0 (M+H)+, retention time 1.27 minutes.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08846661B2uspto-grants-2014_09